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Zenker’s Diverticulum : Causes, Pathophysiology, Symptoms, & Treatment

Zenker’s Diverticulum (Pharyngoesophageal Diverticulum, Pharyngeal Pouch, Hypopharyngeal Diverticulum : Definition, Causes, Pathophysiology, Symptoms, & Treatment

Definition

  • Zenker’s Diverticulum is a pulsion diverticulum of the hypopharynx where a pouch forms in killian’s triangle just above the cricopharyngeal muscle because of increase in intraluminal pressure.
  • Male > Female
  • More common in old age.

Etiopathogenesis

Upper esophageal sphincter dysfunction

Uncoordinated swallowing

Pressure on an area of the pharynx wall ↑

Herniation of wall through killian’s triangle (No muscular support)

Outpouching of the posterior pharyngeal wall

Clinical Features

  • Dysphagia (intermittent)
  • Regurgitation of old food
  • Halitosis (Bad breath)
  • Cough
  • Aspiration & choking

Note: Causes of intermittent dysphagia are

  • Diffuse esophageal spasm (DES) – Most common
  • Zenker’s diverticulum
  • Schatzki ring
  • Eosinophilic esophagitis

Complications

  • Choking
  • Aspiration pneumonitis → Lung abscess
  • Bleeding
  • ↑ risk of cancer (by 5%)

Classification

Morton-Bartney’s Classification of diverticula

  • Small <2 cm
  • Medium 2-4 cm
  • Large >4 cm

Diagnosis

  • Barium Swallow (Investigation of choice)

Treatment

A.  Mild cases

  • Lifestyle changes → Wait & Watch Approach

B. Moderate to Severe cases

Open Method

If <2 cm ⇒ Cricopharyngeal myotomy or neurotoxic injection in cricopharyngeus muscle

If 2-4 cm ⇒  Cricopharyngeal myotomy or neurotoxic injection in cricopharyngeus muscle

+

Diverticulopexy

If >4 cm ⇒ Diverticulectomy + Cricopharyngeal Myotomy

Dohlman Procedure (Endoscopic procedure)

  • Linear staples (nowadays by CO2 LASER)
  • 2-15 cm

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