Coronavirus

Coronaviruses

Coronaviruses

Introduction

  • Coronaviruses are a large family of viruses causing illness in animals or humans.
  • In human, they cause illness ranging from Common Cold to MERS, SARS & COVID-19.

Morphology

  • Enveloped
  • Shape: Carrying petal or club shaped or crown like peplomer spikes giving appearance of Solar Corona.
  • Size: Large (120-160 nm)
  • Symmetry: Helical
  • Genome: Linear, positive sense ss RNA (non- segmented genome)

Classification

Human Coronaviruses which cause human infections. There are 7 recognised human coronaviruses:

  1. Human coronavirus 229E
  2. Human coronavirus NL63
  3. Human coronavirus OC43
  4. Human coronavirus HKU1
  5. SARS-CoV
  6. MERS-CoV
  7. SARS-CoV-2 (Novel coronavirus, 2019-nCoV, Wuhan virus, China virus)

Diseases

  1. SARS-CoV ⇒ SARS (Severe Acute Respiratory Syndrome)
  2. MERS-CoV ⇒ MERS (Middle East Respiratory Syndrome)
  3. SARS-CoV-2 ⇒ Coronavirus Disease 2019 (COVID-19)
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