Silodosin is a adrenergic antagonist (α1-selective blocker), used for benign prostatic hyperplasia (BPH).
Dose: 4-8 mg
Route: Oral
Plasma half-life: 5-21 hours
Duration of action: N/A
Bioavailability: 32%
Chemical formula: C25H32F3N3O4
IUPAC name: 1-(3-hydroxypropyl)-5-[(2R)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]indoline-7-carboxamide
Trade name: Rapaflo, Silodyx, Rapilif, Silodal, Urief, Urorec
Therapeutic uses:
Silodosin is approved for treatment of benign prostatic hyperplasia (BPH).
Note:- It have lesser effect on blood pressure.
Side effects: Adverse effects of Silodosin are as follows:
- Dizziness,
- Drowsiness,
- Insomnia,
- Sexual dysfunction & abnormal / retrograde ejaculation,
- A lack of energy, & weakness
- Headache,
- Orthostatic hypotension,
- Diarrhea,
- Abdominal pain,
- Nasal congestion,
- Prostate specific antigen increased
For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.
