Tropicamide : Therapeutic uses, Clinical uses, Indications, Dosage, Side Effects, Warnings, Interactions, Precautions, Contraindications & Brand names
Tropicamide is a synthetic anti-muscarinic cholinergic antagonist, used as mydriatic and cycloplegic agent for dilating the pupil and paralyzing certain muscles in the eye for diagnostic tests. It may also be used for other conditions as determined by your doctor.
Dose : 0.5-1 % opthalmic solution
Route : Topical
Plasma half-life : ?
Duration of action : 3-6 hours (shorter than that of atropine)
Bioavailability : ?
Chemical formula : C17H20N2O2
IUPAC name : (RS)-N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide
Trade name : Mydriacyl, Mydral, Tropicacyl, Optimide, Tropicamet, Tromide, Tropac-P, Tropicamet plus
Therapeutic uses : Tropicamide is used for mydriasis and cycloplegia in eyes
Side effects : Commonly observed side effects are as follows :
- Transient stinging,
- Slight and transient rise in intraocular pressure
- Redness or conjunctivitis (inflammation)
- Blurring of near vision for a short while after instillation
- Tropicamide may, in very rare cases, cause an attack of acute angle-closure glaucoma. This tends to be in patients with narrow anterior chamber angles, and closure risk must be assessed by the practitioner prior to instillation.
Drug Interactions : Tropicamide may interact with following drugs :
Precautions
Before using this medication, tell your doctor or pharmacist
- If you are allergic to it; or if you have any other allergies.
- Your medical history, especially of personal or family history of glaucoma (angle-closure type), high bp, hyperthyroidism, diabetes, heart disease, Down syndrome, brain damage or spastic paralysis (in children).
Warnings
- FOR TOPICAL OPHTHALMIC USE ONLY. NOT FOR INJECTION
Contraindications
For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.
