Terazosin : Therapeutic uses, Dosage & Side Effects

Terazosin : Therapeutic uses, Dosage & Side Effects

Terazosin is a adrenergic antagonist (α1-selective blocker), used for treatment of high blood pressure & & benign prostatic hyperplasia (BPH).
Dose : 1-10 mg
Route : Oral
Plasma half-life : 12 hours
Duration of action : beyond 18 hours
Bioavailability : ?
Chemical formula : C19H25N5O4
IUPAC name : (RS)-6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine
Trade name : Hytrin, Teralfa, Olyster, Zayasel
Therapeutic uses :
Terazosin is used to treat hypertension & benign prostatic hyperplasia (BPH).
Note:- Terazosin is more popular for use in BHP because of a probable apoptosis promoting effect on prostate.
Directions for use : 

  • Take this medication by mouth with or without food, usually once daily at bedtime as directed by your doctor.
  • If you are taking this drug for the first time, do not take more than 1 milligram to start.

Warnings :  Syncope and “First-Dose” Effect
Side effects : Adverse effects of Terazosin are as follows:

  • Dizziness,
  • A lack of energy,
  • Nasal congestion,
  • Headache,
  • Drowsiness,
  • Orthostatic hypotension,
  • Tachycardia,
  • Sexual dysfunction,
  • Floppy iris syndrome

Contraindications :

  • It is contraindicated in patients known to be hypersensitive to terazosinHCl .

For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.

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