Terazosin : Therapeutic uses, Dosage & Side Effects
Terazosin is a adrenergic antagonist (α1-selective blocker), used for treatment of high blood pressure & & benign prostatic hyperplasia (BPH).
Dose : 1-10 mg
Route : Oral
Plasma half-life : 12 hours
Duration of action : beyond 18 hours
Bioavailability : ?
Chemical formula : C19H25N5O4
IUPAC name : (RS)-6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine
Trade name : Hytrin, Teralfa, Olyster, Zayasel
Therapeutic uses :
Terazosin is used to treat hypertension & benign prostatic hyperplasia (BPH).
Note:- Terazosin is more popular for use in BHP because of a probable apoptosis promoting effect on prostate.
Directions for use :
- Take this medication by mouth with or without food, usually once daily at bedtime as directed by your doctor.
- If you are taking this drug for the first time, do not take more than 1 milligram to start.
Warnings : Syncope and “First-Dose” Effect
Side effects : Adverse effects of Terazosin are as follows:
- A lack of energy,
- Nasal congestion,
- Orthostatic hypotension,
- Sexual dysfunction,
- Floppy iris syndrome
- It is contraindicated in patients known to be hypersensitive to terazosinHCl .
For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.