Drugs

Sertindole : Therapeutic uses, Dosage & Side Effects

Sertindole : Therapeutic uses, Dosage & Side Effects

Sertindole is a antipsychotic drug, used in the treatment of schizophrenia.
Dose : 4-16 mg
Route : Oral
Plasma Half-life : 3 days
Duration of action : Long
Bioavailability : 75%
Chemical formula : C24H26ClFN4O
IUPAC name : 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one
Trade name : Serdolect, Serlect
Therapeutic uses :
Sertindole is indicated as anti-psychotic drug for treating psychoses particularly Schizophrenia.
Points of interest :

  • It is not approved for use in the United States and was discontinued in Australia in January 2014.

Side effects : It may produce following side effects:

  • Headache,
  • Ejaculation failure,
  • Insomnia,
  • Dizziness,
  • Urine that tests positive for red and/or white blood cells,
  • Sedation,
  • Erectile dysfunction,
  • Orthostatic hypotension,
  • Weight gain,
  • Rarely EPS Extra pyramidal symptoms

Contraindications :
For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.

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