Sertindole : Therapeutic uses, Dosage & Side Effects
Sertindole is a antipsychotic drug, used in the treatment of schizophrenia.
Dose : 4-16 mg
Route : Oral
Plasma Half-life : 3 days
Duration of action : Long
Bioavailability : 75%
Chemical formula : C24H26ClFN4O
IUPAC name : 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one
Trade name : Serdolect, Serlect
Therapeutic uses :
Sertindole is indicated as anti-psychotic drug for treating psychoses particularly Schizophrenia.
Points of interest :
- It is not approved for use in the United States and was discontinued in Australia in January 2014.
Side effects : It may produce following side effects:
- Headache,
- Ejaculation failure,
- Insomnia,
- Dizziness,
- Urine that tests positive for red and/or white blood cells,
- Sedation,
- Erectile dysfunction,
- Orthostatic hypotension,
- Weight gain,
- Rarely EPS Extra pyramidal symptoms
Contraindications :
For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.