Drugs

Levocetirizine : Uses, Dosage, Side Effects, Interactions, & Contraindications

Levocetirizine : Therapeutic uses, Clinical uses, Indications, Dosage, Side Effects, Warnings, Interactions, Precautions, Contraindications & Brand names

Levocetirizine (active R(-) enantiomer of cetirizine) is a second generation H1- receptor blocker (Anti-histamine), useful in abolishing the symptoms of the allergic reactions like-Hey fever (allergic rhinitis / coryza), pallinosis, hives (urticaria/ atopic dermatitis), dermographism, eczema etc.
Dose : 2.5-5 mg
Route : Oral
Plasma half-life : 6-10 hours
Duration of action : 12-24 hours
Bioavailability : High
Chemical formula : C21H25ClN2O3
IUPAC name : 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
Trade name : Levosiz, Levorid, Teczine, Xyzal,  Vozet, UVNIL, Curin, Zival, Zilola, Rinozal, Cezera,  Levazyr, Xusal, Xozal, Xazal, Xuzal, Histisynt
Therapeutic uses : Levocetirizine has following usage :

  • Useful in treating & preventing the allergic reactions like-Hey fever (allergic rhinitis / coryza), pallinosis, hives (urticaria/ atopic dermatitis), dermographism, eczema, sneezing, runny nose, itching, watery eyes, & skin rash and common cold.
  • May be used adjuvant in seasonal asthma.

Note :- In contrast to Cetirizine, it is effective at half the dose and appears to produce few side effects.
Side effects : Second-generation H1-antagonists show very few side effects in converse to First generation; following side effects of levocetirizine may be aobserved:

  1. Drowsiness, dizziness,
  2. Tiredness,
  3. Dry mouth,
  4. Constipation etc.

It have negligible sedation.

Drug Interactions : Levocetirizine  may interact with following drugs :

Precautions

Before using this medication, tell your doctor or pharmacist

  • If you are allergic to it; or if you have any other allergies.
  • Your medical history, especially of urinary problems, kidney disease.

Contraindications

For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.

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