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Indoramin : Therapeutic uses, Dosage & Side Effects

Indoramin is a adrenergic antagonist (α1-selective blocker) & antagonist of histamine H1 and 5-HT receptors as well. It is used to treat high blood pressure, BPH, Raynaud’s phenomenon etc.
Dose: 20-50 mg
Route: Oral
Plasma half-life: N/A
Duration of action: N/A
Chemical formula: C22H25N3O
IUPAC name: N-{1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl}benzamide
Trade name: Baratol, Doralese
Therapeutic uses:
Indoramin has following usage :

  • Used for the treatment of hypertension, Benign prostatic hyperplasia BPH, and in the prophylaxis of migraine.
  • May be used to decreases the incidence of attacks of Raynaud’s phenomenon.

Side effects: Adverse effects of Indoramin are as follows:

  • Sedation,
  • Drowsiness,
  • Dizziness
  • Dry mouth,
  • Failure of ejaculation,
  • Nasal congestion,
  • Headache,
  • Fatigue,
  • Weight gain,
  • Postural hypotension,
  • Diarrhoea,
  • Nausea,
  • Increased need to pass urine,
  • Palpitations.
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