Hyoscine butylbromide : Therapeutic uses, Dosage & Side Effects
Hyoscine butylbromide (scopolamine butylbromide) is a semi-synthetic anti-muscarinic cholinergic antagonist, used to treat crampy abdominal pain, renal colic, and bladder spasms. It is also used to improve a death rattle at the end of life.
Dose : 20-40 mg
Route : Oral, I.M. , I.V. , S.C.
Plasma Half-life : 5 hours
Duration of action : N/A
Bioavailability : <1%
Chemical formula : C21H30NO4+
IUPAC name : [7(S)-(1α,2β,4β,5α,7β)]-9-butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-3-oxa-9-azonitricyclo[3.3.1.0(2,4)]nonane
Trade name : Buscopan
Therapeutic uses : Hyoscine butyl bromide is used for esophageal and gastrointestinal spastic conditions.
Points of interest :
- It is less potent & longer acting than atropine.
Side effects : Commonly observed side effects are as follows :
- Dry mouth,
- Dry skin,
- Sweating,
- Itchy skin rash.
Contraindications :
For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.