Fesoterodine : Therapeutic uses, Clinical uses, Indications, Dosage, Side Effects, Warnings, Interactions, Precautions, Contraindications & Brand names
Fesoterodine is a synthetic anti-muscarinic cholinergic antagonist, used as vesico-selective agent for treating overactive bladder with symptoms of urinary frequency, urgency, and leakage. It may also be used for other conditions as determined by your doctor.
Dose : 4-8 mg
Route : Oral
Plasma Half-life : 7–8 hours (active metabolite)
Duration of action : 6-7 hours
Bioavailability : 52% (active metabolite)
Chemical formula : C26H37NO3
IUPAC name : [2-[(1R)-3-(Di(propan-2-yl)amino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate
Trade name : Toviaz
Therapeutic uses : Fesoterodine is used as vesico-selective agent to treat overactive bladder.
Side effects : Following side effects may be elicited :
- Dry mouth,
- Blurred vision,
Drug Interactions : Fesoterodine may interact with following drugs :
- Potassium tablets/capsules
- Anticholinergic medications such as atropine, scopolamine
- Antihistamines such as diphenhydramine
- Antispasmodics including dicyclomine, belladonna alkaloids).
- Certain azole antifungals such as itraconazole, ketoconazole
Before using this medication, tell your doctor or pharmacist
- If you are allergic to it; or if you have any other allergies.
- Your medical history, especially of urinary problems, GI disease, constipation, narrow-angle glaucoma, kidney disease, liver disease, myasthenia gravis.
- Contraindicated in patients with hypersensitivity to fesoterodines or tolterodine (both are metabolized to 5-hydroxymethyl tolterodine) or any component of the formulation.
- Contraindicated in urinary retention, gastric retention, uncontrolled narrow-angle glaucoma.
For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.