Drugs

Fesoterodine : Uses, Dosage, Side Effects, Interactions, & Contraindications

Fesoterodine : Therapeutic uses, Clinical uses, Indications, Dosage, Side Effects, Warnings, Interactions, Precautions, Contraindications & Brand names

Fesoterodine is a synthetic anti-muscarinic cholinergic antagonist, used as vesico-selective agent for treating overactive bladder with symptoms of urinary frequency, urgency, and leakage. It may also be used for other conditions as determined by your doctor.
Dose : 4-8 mg
Route : Oral
Plasma Half-life : 7–8 hours (active metabolite)
Duration of action : 6-7 hours
Bioavailability : 52% (active metabolite)
Chemical formula : C26H37NO3
IUPAC name : [2-[(1R)-3-(Di(propan-2-yl)amino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate
Trade name : Toviaz
Therapeutic uses : Fesoterodine is used as vesico-selective agent to treat overactive bladder.
Side effects : Following side effects may be elicited :

  • Dry mouth,
  • Constipation,
  • Blurred vision,
  • Tachycardia.

Drug Interactions : Fesoterodine may interact with following drugs :

  • Ramlintide
  • Potassium tablets/capsules
  • Anticholinergic medications such as atropine, scopolamine
  • Antihistamines such as diphenhydramine
  • Antispasmodics including dicyclomine, belladonna alkaloids).
  • Certain azole antifungals such as itraconazole, ketoconazole

Precautions

Before using this medication, tell your doctor or pharmacist

  • If you are allergic to it; or if you have any other allergies.
  • Your medical history, especially of urinary problems, GI disease, constipation, narrow-angle glaucoma, kidney disease, liver disease, myasthenia gravis.

Contraindications

  • Contraindicated in patients  with hypersensitivity to fesoterodines or tolterodine (both are metabolized to 5-hydroxymethyl tolterodine) or any component of the formulation.
  • Contraindicated in urinary retention, gastric retention, uncontrolled narrow-angle glaucoma.

For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.

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