Ebola Virus (EV)

Ebola Virus EV

  • Ebolaviruses have linear, nonsegmented, single-stranded, negative-sense RNA genomes that are ~19 kb in length. These genomes contain six or seven genes that encode the following seven structural proteins: nucleoprotein, polymerase cofactor (VP35), matrix protein (VP40), glycoprotein (GP1,2), transcriptional cofactor (VP30), secondary matrix protein (VP24), and RNA-dependent RNA polymerase (L protein).
  • Ebolaviruses also encode three nonstructural proteins of unknown function (sGP, ssGP, and Δ-peptide).
  • Family : Filoviridae
  • Genus : Ebolaviruses
  • E.g. of Ebolaviruses : Reston virus (RESTV), Bundibugyo virus (BDBV), Ebola virus (EBOV), Sudan virus (SUDV), and Taï Forest virus (TAFV)
    Reston virus (RESTV) is not pathogenic for humans.
    Remaining four ebolaviruses—Bundibugyo virus (BDBV), Ebola virus (EBOV), Sudan virus (SUDV), and Taï Forest virus (TAFV)—cause Ebola virus disease (EVD).
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