Diclofenac : Therapeutic uses, Dosage & Side Effects

Diclofenac : Therapeutic uses, Dosage & Side Effects

Diclofenac is a Aryl-acetic acid derivatives & non-selective COX inhibitor (traditional NSAID), used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis.
Dose : 25-50 mg (Oral), 75 mg deep i.m.
Route : Oral, IM, IV, Rectal, Topical
Plasma Half-life : 1.2-2 hhours (35% of the drug enters enterohepatic recirculation)
Duration of action : ?
Bioavailability : ?
Chemical formula : C14H11Cl2NO2
IUPAC name : [2-(2,6-Dichloroanilino)phenyl]acetic acid
Trade name : Cataflam, Flector, Pennsaid, Voltaren, Voveran, Diclonac, Movonac, Diclomax, Voltaflam, Ultra-K, Voveran, Voveran Optha eye drop, Emulgel, Relaxyl gel, Diclonac gel, Aclonac, Cataflam, Cambia, Voltaren-XR, Zipsor, Zorvolex, Dyloject
Therapeutic uses : Diclofenac sodium has following usage :

  • Used as Anti-inflammatory, Analgesic drug in rheumatoid and osteoarthritis, bursitis, ankylosing spondylitis, toothache, dysmenorrhoea, post-traumatic and postoperative inflammatory conditions-affords quick relief of pain and wound edema.
  • Used as Antipyretic agent to treat fever.
    Diclofenac is among the most extensively used NSAID.

Side effects : Adverse effects of diclofenac are generally mild. Diclofenac may cause following Side effects :

  • Epigastric pain,
  • Nausea,
  • Headache,
  • Dizziness,
  • Rashes,
  • Gastric ulceration,
  • Bleeding,
  • Reversible elevation of serum aminotransferases.

Contraindications :
For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.

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