Cetirizine : Therapeutic uses, Clinical uses, Indications, Dosage, Side Effects, Warnings, Interactions, Precautions, Contraindications & Brand names
Cetirizine (Metabolite of hydroxyzine) is a second generation H1- receptor blocker (Anti-histamine), useful in treating the allergic reactions like-Hey fever, eczema etc.
Dose : 5-10 mg
Route : Oral
Plasma half-life : 8.3 hours
Duration of action : 12-24 hours
Bioavailability : Excellent
Chemical formula : C21H25ClN2O3
IUPAC name : (±)-[2-[4-[(4-chlorophenyl)phenylmethyl]-1- piperazinyl]ethoxy]acetic acid
Trade name : Alatrol, Alerid, Alzene, Cetirin, Cetirizin, Cetirizina, Cetzine, Cezin, Histazine, Humex, Letizen, Razene, Zetop, Zirtek, Zodac, Zyllergy, Zynor, Zyrlek, Zirtin, Sizon, Zyrtec, Zirtec, Reactine
Therapeutic uses : Cetirizine has following usage :
- Useful in treating & preventing the allergic reactions like-Hey fever (allergic rhinitis / coryza), pallinosis, hives (urticaria/ atopic dermatitis), dermographism, eczema, sneezing, runny nose, itching, watery eyes, & skin rash and common cold.
- May be used adjuvant in seasonal asthma.
- It have mild sedation because of negligible penetration into the brain but is associated with a somewhat higher incidence of drowsiness than the other second-generation H1 antagonists..
Side effects : Second-generation H1-antagonists show very few side effects in converse to First generation. Following side effects may be provoked:
- Drowsiness, dizziness,
- Tiredness,
- Dry mouth,
- Weakness,
- Constipation
- Stomach pain etc.
Drug Interactions : Cetirizine may interact with following drugs :
Precautions
Before using this medication, tell your doctor or pharmacist
- If you are allergic to it; or if you have any other allergies.
- Your medical history, especially of urinary problems, kidney disease, liver disease.
For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.
