Drugs

Biperiden : Uses, Dosage, Side Effects, Interactions, & Contraindications

Biperiden : Therapeutic uses, Clinical uses, Indications, Dosage, Side Effects, Warnings, Interactions, Precautions, Contraindications & Brand names

Biperiden is a synthetic anti-muscarinic cholinergic Antagonist, used as adjunct to treat Parkinson’s disease, Parkinsonian syndromes, including antipsychoticinduced extrapyramidal symptoms.
Dose : 2-10 mg
Route : Oral, Intra-muscular(I.M.), Intra-venous(I.V.)
Plasma half-life : 18-24 hours
Duration of action : 18-24 hours
Bioavailability : 33 ± 5% (oral)
Chemical formula : C21H29NO
IUPAC name : (1RS,2SR,4RS)-1-(bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin- 1-yl)propan-1-ol
Trade name : Dyskinon, Akineton
Therapeutic uses : Biperiden is used as adjunct to treat Parkinson’s disease, Parkinsonian syndromes, including antipsychoticinduced extrapyramidal symptoms.
Side effects : Commonly observed side effects are as follows :

  • Xerostomia (dryness of the mouth),
  • Mood alterations,
  • Visual problems,
  • Interfere with gastrointestinal peristalsis and are contraindicated in patients with glaucoma, prostatic hyperplasia, or pyloric stenosis,
  • Urinary retention,
  • Constipation,
  • Impairment of memory and organic confusional states (more common in the elderly.)

Drug Interactions : Biperiden may interact with following drugs :

Precautions

Before using this medication, tell your doctor or pharmacist

  • If you are allergic to it; or if you have any other allergies.
  • Your medical history.

Contraindications

  • Narrow angle glaucoma.
  • Bowel obstruction or megacolon.
  • Known hypersensitivity to biperiden or any ingredient in the formulation.

For detailed query or in case of uncertainty, Always consult your doctor or pharmacist.

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