Drugs

Antiepileptic Drugs : Classification, Uses, Side Effects, & Contraindications

Antiepileptic Drugs : Definition, Classification, Example, Mechanism of Action, Uses, Side Effects, Contraindications, & Interactions

Introduction

  • Epilepsy is defined as a condition characterised by recurrent (two or more) unprovoked seizures.

Classification

Class Drugs
Barbiturates Phenobarbital
Deoxybarbiturates Primidone
Hydantoin Phenytoin
Fosphenytoin
Iminostilbene Carbamazepine
Oxcarbazepine
Eslicarbazepine
Succinimide Ethosuximide
Caboxylic acid Divalproex
Sodium valproate
Phenyl triazine Lamotrigine
Cyclic GABA Analogue Gabapentin
Benzodiazepines Clonazepam
Diazepam
Lorazepam
Clobazam
Newer Drugs Vigabatrin
Topiramate
Tiagabine
Zonisamide,
Levetiracetam
Ezogabine
Felbamate
Lacosamide
Perampanel
Pregabalin
Rufinamide

Drugs for various epilepsies

Type of epilepsy First-line drugs Alternative drugs
Generalised
tonic-clonic seizures (GTCS)
Valproic acid
Carbamazepine
Phenobarbital
Lamotrigine
Topiramate
Felbamate
Partial epilepsy Carbamazepine
Phenytoin
Oxcarbazepin
Lamotrigine
Levetiracetam
Phenobarbital
Gabapentin
Topiramate
Absence epilepsy Ethosuximide
Valproic acid
Lamotrigine
Clonazepam
Atypical absence,
Myoclonic & Atonic epilepsy
Valproic acid Lamotrigine
Clonazepam
Topiramate (as adjunct)

For detailed query about Uses, Side Effects, Contraindications, Interactions of antiepileptic drugs, refer to individual drugs.

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