Clinical Disorders

Acne Vulgaris : Causes, Symptoms, Treatment, & Prevention

Acne Vulgaris : Definition, Etiology, Epidemiology, Symptoms, Management, & Prevention

Definition

  • Acne Vulgaris is an inflammatory disease of the pilosebaceous follicle characterized by comedones, papules, pustules, cysts and scars.

Epidemiology

  • Nearly all teenagers (>80% ) aged 13- 18 years.

Causes

  • Hormonal (androgen)
  • Increased sebum production
  • Poral occlusion
  • Abnormal follicular keratinization
  • Bacterial colonization (Propionibacterium acnes)
  • Inflammation

Clinical Presentation

  • Non-inflammatory lesions (mild acne) – open and closed comedones (blackheads and whiteheads)
  • Inflammatory lesions (moderate and severe acne) – papules, pustules, nodules, and cysts
  • Commonly affects the face, chest and upper back

Course

  • Acne vulgaris clears by the age of 23–25 years in 90% of patients, but some 5% of women and 1% of men still need treatment in their thirties or even forties.

Investigations

  • None are usually necessary.

Management

A. General measures

  • No specific food which cause acne.
  • Treatment needs to be continued for at least 6 weeks to produce effect.

B. Local treatment (for mild acne)

1. Cleansing: Regular gentle cleansing with soap and water should be encouraged, to remove surface sebum.

2. Topical therapies

C. Systemic treatment (for moderate to severe acne)

1. Oral antibiotics

2. Hormonal

  • Anti-androgens (in females)

3. Oral retinoids (for severe acne)

D. Physical

  • LASER treatment

Acne scar treatment

  • Dermabrasion
  • Lasers
  • Dermal fillers

Complications

  • Post-inflammatory hyperpigmentation
  • Scarring
  • Deformity
  • Psychological and social effects

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